Outbreak Detection & Reporting

Learn how potential outbreaks are identified and get practical advice for improving detection and reporting.


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Relevant dates
Last updated: June 30, 2024
Published: December 18, 2024

Chapter Summary

Detection and reporting provide the foundation for a healthcare outbreak response, triggering activities aimed at assessing the situation, implementing control measures, and halting disease transmission.

In Chapter 4, Outbreak Detection & Reporting, we examine the two primary pathways for recognizing potential outbreaks, detection via reports and through use of surveillance data. Definitions of sentinel cases, clusters, and outbreaks are described. 

The section on direct reporting of outbreaks includes information on reporting within a healthcare facility and reporting to public health, entities that can report to public health, and types of events that may be reported. This is followed by an overview of the use of routine surveillance systems for cluster and outbreak detection. 

Strengths and limitations, key determinants of successful detection, and model practices are described for both types of detection methods. Health departments can improve outbreak detection by regularly communicating reporting mechanisms and expectations to hospitals, long term care facilities and other provider types; consider establishing thresholds for reporting that are specific to commonly encountered conditions.

The chapter concludes with some considerations for detecting and reporting multifacility and multijurisdictional outbreaks, a topic that is unpacked further in Supplement B, Infection Control Breach Investigations.

 

Change Log

As advances occur in outbreak protocols, this guidance document will be updated. Previous changes can be tracked below:

  • 2nd Edition – Published June 2024
  • 1st Edition – Published October 2022
  • URLs in this document are valid as of April 30, 2024.  

Chapter References

  1. Centers for Medicare and Medicaid Services (CMS), Center for Clinical Standards and
    Quality/Survey & Certification Group. Infection control breaches which warrant referral to public
    health authorities. May 30, 2014. Revised October 28, 2016.
    https://www.cms.gov/Medicare/Provider-Enrollment-andCertification/SurveyCertificationGenInfo/Downloads/Survey-and-Cert-Letter-14-36.pdf
  2. Christenson BE, Fagan RP. Healthcare Settings. In: Rasmussen SA, Goodman RA, eds. The CDC
    Field Epidemiology Manual. US Department of Health and Human Services Centers for Disease
    Control and Prevention (CDC); 2018:chap 18. https://www.cdc.gov/eis/field-epimanual/chapters/Healthcare-Settings.html
  3. Centers for Disease Control and Prevention (CDC). Principles of Epidemiology in Public Health
    Practice: An Introduction to Applied Epidemiology and Biostatistics, 3rd Edition. October 2006.
    https://www.cdc.gov/csels/dsepd/ss1978/index.html
  4. Lyman MM, Grigg C, Kinsey CB, et al. Invasive nontuberculous mycobacterial infections among
    cardiothoracic surgical patients exposed to heater–cooler devices. Emerg Infect Dis.
    2017;23(5):796–805. doi: 10.3201/eid2305.161899
  5. Navon L, Clegg WJ, Morgan J, et al. Notes from the field: investigation of Elizabethkingia
    anophelis cluster — Illinois, 2014–2016. MMWR Morb Mortal Wkly Rep. 2016;65(48):1380–
    1381. doi: 10.15585/mmwr.mm6548a6
  6. Kainer MA, Reagan DR, Nguyen DB, et al. Fungal infections associated with contaminated
    methylprednisolone in Tennessee. N Engl J Med. 2012;367(23): 2194–2203. doi:
    10.1056/NEJMoa1212972
  7. Franklin SM, Crist MB, Perkins KM, Perz JF. Outbreak response capacity assessments and
    improvements among public health department health care-associated infection programs—
    United States, 2015-2017. J Public Health Manag Pract. 2022;28(2):116-125. doi:
    10.1097/PHH.0000000000001148
  8. Lee TB, Montgomery OG, Marx J, Olmsted RN, Scheckler WE. Recommended practices for
    surveillance: Association for Professionals in Infection Control and Epidemiology (APIC), Inc. Am
    J Infect Control. 2007;35(7):427-440. doi: 10.1016/j.ajic.2007.07.002
  9. Greene LR, Cain TA, Khoury R, Krystofiak SP, Patrick M, Streed S. APIC Position Paper: The
    importance of surveillance technologies in the prevention of healthcare-associated infections
    (HAIs). Association for Professionals in Infection Control and Epidemiology (APIC). May 29, 2009.
    http://www.apic.org/Resource_/TinyMceFileManager/AdvocacyPDFs/Surveillance_Technologies_position_paper_2009-5_29_09.pdf
  10. . Natale A, Stelling J, Meledandri M, Messenger LA, D'Ancona F. Use of WHONET-SaTScan system for simulated real-time detection of antimicrobial resistance clusters in a hospital in Italy, 2012 to 2014. Euro Surveill. 2017;22(11):30484. doi: 10.2807/1560-7917.ES.2017.22.11.30484 
  11. Bamberg W, Kainer M, Bryan N, Anderson M. Assessment of HAI/AR outbreak detection data, tools, and barriers. Poster (Board 183) presentation at: International Conference on Emerging Infectious Diseases; Aug 2018; Atlanta, Georgia. https://www.cdc.gov/iceid/docs/ICEID-2018- program-book-P.pdf
  12. Leclère B, Buckeridge DL, Boëlle P-Y, Astagneau P, Lepelletier D. Automated detection of hospital outbreaks: a systematic review of methods. PLoS One. 2017;12(4):e0176438. doi: 10.1371/journal.pone.0176438
  13. Centers for Disease Control and Prevention (CDC). U.S. & Global Antimicrobial Resistance Laboratory Networks. How to participate: lab testing. https://www.cdc.gov/drugresistance/laboratories/AR-lab-network-testing-details.html
  14. Mikosz CA, Smith RM, Kim M, Tyson C, Lee EH, Adams E, et al. Fungal endophthalmitis associated with compounded products. Emerg Infect Dis. 2014;20(2):248-256. doi: 10.3201/eid2002.131257
  15. Dolan SA, Littlehorn C, Glodé MP, et al. Association of Bacillus cereus infection with contaminated alcohol prep pads. Infect Control Hosp Epidemiol. 2012;33(7):666-671. doi: 10.1086/666334
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