Investigation Resources > All Pathogens & Diseases > Clostridioides difficile

Clostridioides difficile

Also referred to as 'C. diff' or CDI; formerly Clostridium difficile 

Published
December 26, 2024
Last updated
May 24, 2024

About CDI

Clostridioides difficile is a type of spore-forming bacteria that can cause life-threatening diarrhea and colitis. C. difficile infection (CDI) is related to antibiotic exposure and is a frequent cause of healthcare-associated infections. CDI can spread from patient to patient and occasionally results in outbreaks among people being cared for in nursing homes and hospitals. 

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Featured New Updated

Clostridioides difficile Infection (CDI): Recommendations for Healthcare Outbreak Response

This CORHA-developed product includes thresholds for investigation and reporting of a possible Clostridioides difficile infection (CDI) outbreak. Additional sections outline important actions and considerations for CDI outbreak investigation and control. This document includes listings of key references and supplemental resources.

New Updated

Slide Presentation: Investigating C. difficile Infections

 By California Department of Public Health

This educational resource reviews steps for CDI cluster and outbreak response

New Updated

C. diff Guidelines and Prevention Resources

 By CDC

New Updated

Compendium of Strategies to Prevent Clostridium difficile Infections in Acute Care Hospitals

 By IDSA; SHEA

Principles & Practices

Comprehensive information to build, standardize or improve practices related to HAI/AR outbreak detection, reporting, investigation, or control.

Clostridioides difficile Outbreak Reports & News